Areas of Expertise

Target identification and validation

Genomics

Knowledge mining

Functional phenotypic screens

We have strong expertise in target identification in multiple therapeutic areas including oncology, rare diseases, disorders of liver, kidney, CNS, eye, and immunology. From genomics data analysis, to literature mining, to the design and analysis of functional phenotypic screens, our team can apply state-of-the art, or create de novo methods, to find novel therapeutic targets in your therapeutic area. From genomics data analysis, to literature mining, to the design and analysis of functional phenotypic screens, our team can apply state-of-the art, or create de novo, methods to find novel therapeutic targets in your therapeutic area.

Designing and analyzing `omics experiments

DNA, RNA and protein profiling

Design of experiments

Rigorous data analysis

Biological interpretation

Good results require excellent experimental design. Our team has expertise in working directly with you to design the best possible experiments, with the right control groups, appropriate statistical power, and proper controls for confounding factors and batch effects. From here, we work in collaboration with project teams, analyzing and interpreting data in a personalized fashion for your therapeutic modality. From class comparisons, to the prediction of categorical and quantitative traits, we will help you get most out of your data.

Pre-clinical drug discovery

Design of experiments

Discovery of pharmacodynamic (PD) biomarkers

Molecular mechanism of action (MoA)

Drug sensitivity analysis (single agents and combinations)

Resistance mechanisms

We have substantial expertise in drug discovery for multiple therapeutic modalities (small molecule, antibody, oligonucleotide) and will work with you on solving your project needs.

Translational and clinical program analyses

Translational PD biomarkers

Resistance mechanisms

Indications discovery

Patient selection strategies

Support for client’s growth

Recruiting and mentoring top bioinformatics talent

We understand that companies need change as they grow and advance into new stages of clinical and commercial development. With extensive experience in recruiting and training, we can help you to hire and mentor top bioinformatics talent to address your growth needs.